At higher dosages, attachment into the delta-opioid receptors raises, and at quite substantial doses, we determine attachment into the mu receptors – consequently, the stimulant effects. Mitragynine in reduced doses creates a yohimbine-like agreeing into alpha-adrenergic receptors(and partial attaching into the delta-opioid receptors) – consequently, the arousing effects at lower doses. Much like opiates, kratom from massive doses may lead to nausea and
